Scientists grew up a human liver from stem cells

At the International conference on research of stem cells in Yokohama Japanese scientists presented results of development of innovative technology on creation of an artificial liver.

Scientists from university of Yokohama (Yokohama City University) grew up a human liver from stem cells. However, to replace it to the patient yet it will not be possible. First, the received structure too small – only about five millimeters in diameter, and secondly, it was grown up in the head of an experimental mouse. Besides, the body which has been grown up by Hideki of Taniguti and Takanori Takebe, still it is necessary to check on "professional suitability", that is, whether it carries out necessary functions. Nevertheless, already now many experts call work of Japanese as break in transplantology. In the work scientists used the induced plyuripotentny stem cells which were programmed" on transformation into cells of a liver. In addition scientists added cages germinal connecting a fabric — mesenchymas and cages from umbilical cord blood. «We mixed some types of cages, and they independently gathered to structures almost identical to fabrics of a human liver. Ourselves were surprised!. Later researchers replaced the received structures in a skull of live mice with a heavy immunodeficiency. Plentiful inflow of blood to a brain of small animals promoted the strengthened growth of new body, and the weakened immunity couldn't cause rejection brought from the outside of fabrics» — Takebe told. In 48 hours of a cage began to be formed in a tiny liver. The quantity and structure of a glycogen and amino acids completely corresponded to human body. «The liver received by us still is far from ideal — scientists speak. – We still should find a way of a reconstruction of bilious channels and increase in the sizes of body». Japanese presented results of work at the International conference on research of stem cells in Yokohama (ISSCR 2012). For this reason the detailed description isn't published yet in reviewed magazines. Now researchers of the Country of a rising sun carry out the careful analysis of the received body to understand true value of the work.