Stem cells will receive from uterine pipes

The Brazilian scientists suggested to use the fabrics received at amputation of a uterus, for receiving stem cells, reports the Air Force. Work of experts from São Paulo University (University of Sao Paulo) was published in The Journal of Translational Medicine.

Researchers could allocate and multiply on a nutrient medium multipotentny stem cells from fabrics of uterine pipes which leave together with a uterus or at surgical sterilization. Further these stem cells can be used for receiving hryashchevy, bone, fatty and muscular fabrics.

According to researchers, opening can be used for development of new methods of treatment of such diseases as arthritis, and also as a source of mezenkhimny stem cells. These cages will help with studying of mechanisms of development of infertility at women.

The previous researches showed possibility of receiving multipotentny stem cells from various fabrics of an organism (fatty, muscular, hryashchevy, bone and others). Making comments on work of the Brazilian scientists, the employee of Royal college of London (Kings College London) Stefen Minger (Stephen Minger) noted its ethical value. However he added that receiving stem cells from a fatty fabric or a marrow is more available and less travmatichny for the person.

Controllable clinical researches

Use of an umbilical blood in the future while vaguely. There is a number of promising researches, but the checked ways of treatment with use of an umbilical blood are described here. The bank of the umbilical blood, declaring that he knows precisely how stem cells in the future will be used, isn't honest with you.
Stem cells can recycle heart after the suffered heart attack


1. Treatment Potential treatment of illnesses of heart is based on ability of stem cells to restore a pericardium.
2. A cellular injection Stem cells are entered through a catheter into heart directly right after a heart attack or when heart very much weakened and became inactive to swing blood properly.
3. New life Results show that stem cells can treat the damaged fabrics but while there is no confidence of, whether there are stem cells cells of the adult person or they stimulate division and regeneration of already existing cells of heart.

On March 18 2011 — Researchers of stem cells showed for the first time that the stem cells entered into increased heart, reduced its volume, a cicatricial fabric and improved functioning of the struck sites of heart. The received results of the small experiment which has been carried out in Interdistsiplinarn institute of stem cells (Interdisciplinary Stem Cell Institute) at Miami university, Miller's (University of Miami Miller School of Medicine) medical school, are published on March 17 in Circulation Research release: Journal of the American Heart Association.?? “Even at early stages of this research,” Joshua M. Her, the senior head of research and director Interdistsiplinarnogo of institute of stem cells speaks, ”its results sound is promising for more than five

million Americans with the increased heart because of the suffered heart attack.” Such patients are subject to risk of premature death, are invalid and need frequent hospitalization. Traditionally treatment is carried out in two directions — lifelong acceptance of drugs and surgical intervention, for example, a heart transplantation.

On October 12 2010: Scientists declared on Monday that they entered into Friday stem cells to the patient with the damaged spinal cord, having given that began to first-ever clinical research of therapy by stem cells of a human embryo.

The patient was on treatment in Shepherd Center, the center of violations back and a brain in Atlanta.

In spite of the fact that the experience which is carried out by Geron Corp. Menlo Park, California, was at early stages — on purpose to investigate treatment about its safety — this event represents the first step in research of embryonic stem cells, this corporation already for many years studied cellular potential in treatment of damages back могзга, diabetes and a number of neurodegenerate diseases.

The bone can do of fat

The American scientists developed an improbable method of restoration of a bone fabric. They allocated stem cells from a fatty fabric and grew up from them a bone.
Methods of restoration of a bone fabric which are used now, are imperfect. Scientists managed to create a new reliable method of cultivation of a bone from the stem cells received from a fatty fabric.

Scientists hope that for restoration of a bone fabric the doctor will need to receive a fatty fabric of the patient, to allocate stem cells and to place them there where it is necessary to grow up a bone.

Unlike traditional methods which are used for restoration of the bones, the new method allows to grow up a bone in short terms and more quality.

Introduction of cages of an umbilical blood promotes restoration after a stroke

The cages of an umbilical blood entered intravenously get into a brain, migrate and improve a functional condition after the suffered stroke. To such conclusion the group of researchers after experiments on rats at whom the ischemic stroke was simulated came. In 7 days after introduction of human cages considerable improvement of behavioural parameters of animals was noted. Human cages got into the struck site of a brain of rats and appeared are capable to be differentiated in nervous cages. According to the conclusion of authors, transplantation of cages of an umbilical blood can find application in treatment of the patients who have had a stroke.

Stem cells of an umbilical blood are capable to restore an eye fabric

The umbilical blood contains a significant amount of the cages predecessors, capable to form new blood vessels. In the work published in the Circulation Research magazine (2003, 93:e51-62), svezhevydelenny cages of an umbilical blood entered into a muscle operating movement of an eye (at mice). Formation of new vessels and new muscular fibers was as a result observed. Similar properties of cages of an umbilical blood remained and after their additional reproduction in culture. The obtained data showed high plasticity of cages of an umbilical blood and possibility of their application for transplantation at ophthalmologic violations.

Physicians use the best efforts, that stem cells found application quicker. And whether any real help is possible from society?

Natalia YEPIFANOV
In discussion take part:

The academician of the Russian Academy of Medical Science, the corresponding member of the Russian Academy of Sciences, the director of Institute of experimental cardiology Kardiokompleksa of MZ Russian Federation in Moscow, professor Vladimir Nikolaevich Smirnov.

The doctor of medical sciences, the corresponding member of the Russian Academy of Medical Science, the head of office of chemotherapy гемобластозов and transplantations of a marrow of the Gematologichesky Russian Academy of Medical Science scientific center in Moscow, the professor Valery Grigoryevich Savchenko. The candidate of medical sciences, the Dr.Sci.Biol., the leading research associate of Scientific and practical laboratory of stem cells of the person of Institute of experimental cardiology Kardiokompleksa MZ Russian Federation in Moscow Yury Askoldovich Romanov.

– Stem cells are the still far myth or already reality? There are any practical results of their use?

V. Savchenko: Today stem cells are widely and successfully applied, as a matter of fact, only in hematology. More precisely, in a blood cancer therapy. With their help we achieve amazing results. If in certain cases efficiency of chemotherapy at cancer patients makes only 30 %, with application of stem cells – 60 %.

V. Smirnov: Some time ago the European committee on treatment of multiple sclerosis published recommendations about application of stem cells in treatment of this disease. Here stem cells "do" what couldn't achieve several years ago. Namely – the illness fades at a certain level and doesn't progress. This great achievement.

– What is the stem cells and in what their curative force consists?

V. Smirnov: Each of us has stem cells. These are peculiar spare parts which help an organism to be restored if in its harmonious work there was any failure. Cages happen two types: krovetvorny and stromalny. The first serve only for formation of the new blood cells, the second – for all other fabrics. Krovetvornye stem cells contain in a marrow

– "the central warehouse of spare parts". A few stromalny cages are in each fabric – on a case of updating or small breakage, and their main quantity – all in the same marrow.

Uniqueness of stem cells – in their "immortality". The matter is that they are capable to share not how usual cages which breed symmetrically. At division of one cage there are two native "daughters" similar to "mother". Stem cells usually share in a different way: they too give two affiliated. But one of them is similar parent, and another – absolutely other, is formed of it a concrete fabric. Such division gives the chance to help another and at the same time to keep itself – therefore stem cells there lives so much, how many the person.

In recent years treatment, to be exact, change of stem cells is a perspective way of fight against various illnesses.

– If it is change, means, cages need to be taken at first from where. What it for sources?

ISKCh knows how to profit by a cage

The company Institute of stem cells of the person held presentation following the results of two years passed after IPO, and also presented development strategy till 2016. In the next years very active growth is supposed, and it should be reflected in company capitalization positively.
In my opinion, prospects of development of a portfolio of projects as a financial and operational performance of the company completely depends on it are especially interesting to investors and shareholders. If before IPO it had only one product in the market, now such products already four, and by their 2016 will be nine that considerably will increase growth rates of revenue.

By 2016 the volume of revenue is predicted at level of 3,6 billion roubles, and in 2012 it is expected at a rate of 390 million roubles, that is all for 4 years will be shown more than ninefold growth. I expect that in 2011 the revenue will make about 180 million roubles at profitability on EBITDA at level about 5 %.

The main volume of revenue of ISKCh is brought now by services of a fence, allocation and storage of stem cells of an umbilical blood which according to the last reporting on RSBU in 9 months 2011 make 96 % from total amount. Another 4,3 % — the income of SPRS therapy service, in 2011 they will make about 5 %. Thus, 95 % from revenue bring project services Gemabank. In 2012 its share from this service will make about 8 %, that is about 31 million roubles, by 2016 it will decrease to 6,6 %.



Thus the number of the signed contracts at Gemabank increases. According to preliminary data, in their 2011 became more for 6,4 %, and now the company borrows on the Russian market of 56 % that also assumes increase in a share. Stability in this segment is very important now for the company as "Neovaskulgen's" sales which should begin in the 2nd quarter 2012, big levels hardly it is quickly reached, but in the long-term period this preparation becomes one of major factors for revenue growth.

So, in the current year a share of sale of this preparation in total amount of revenue will make about 9 %, that is 35 million roubles, and in four years it will make already 45 %. As "Neovaskulgen's" analogs will appear in Russia only in 3-5 years, the company has excellent prospects for receiving a big segment in the market in the future. Thus by 2016 a share in revenue of ISKCh from the project Gemabank will decrease to 15 % against 74 % which are expected in 2012. In new year sales according to Gemaskrin's project which following the results of a year will bring about 5 % from total sales were started, and to the 2016th this share will grow to 16 %. Besides, in 2012 sales according to several projects will begin. In particular, on SPRG therapy, a bankirovaniye of reproductive cages and fabrics and equipment distribution for cellular processing (Cytori).

Such diversification of a portfolio of projects is the main for stable development that will allow the company to increase considerably and financial results. If in 2012 profitability on EBITDA is expected at level of 5 %, that, thanks to active development of projects and successful