Scientists learned to do cages deckman DNA without participation

Scientists developed a new method of transformation of cages in deckman DNA without use. Article with the description of technology is published in the Cell Stem Cell magazine. Briefly results of researchers are described by the The Scientist magazine. Stem cells differ from "usual" subjects that are capable to develop on several ways. In other words, they can turn into various types of cages. The destiny of not stem cells is rigidly predetermined. As limiters certain updatings of DNA which stem cells don't have act. In recent years scientists developed some ways of reprogramming of not stem cells. All of them demanded introduction in a cage of certain genes. Addition of an alien genetic material does techniques potentially dangerous as DNA can be built in a genome of a cage and cause serious violations of its work. The majority of techniques means DNA introduction by means of the special infectious agent, and it essentially increases probability of a vstroyka. Authors of new research could turn фибробласты into plyuripotentny stem cells, without entering into their kernels of DNA. Researchers used "cocktail" from several transkriptsionny factors. This term the squirrels promoting reading of information from a certain site of a genome call. Proteins in a large number made genetically modified cages of an intestinal stick of Escherichia coli. Researchers allocated them, cleared and added in culture фибробластов - specialized cages of a connecting fabric. In comparison with the technology, using infectious agents, efficiency of transformation was 10 times less - 0,006 percent against 0,067 percent. Nevertheless, the method has big prospects for use in medical practice. The safe way of receiving stem cells is necessary, for example, for cultivation of a healthy warm fabric instead of the damaged.