понедельник, 22 октября 2012 г.
Scientists study "garbage DNA" the person
The most part of a human genome is presented so-called to "garbage DNA" - free scraps of a genetic code. The last researches of the international scientific group showed that the essential part of this material is formed by DNA of various viruses.
Under the direction of the professor of biology of Cedric Feskotta from the Texas university the group of scientists of the USA and Japan found out that in a genome of the person and some mammals of a chain of DNA contain inserts of a virus of Born, replication and which transmission can occur in cellular kernels. Together with the Japanese colleague professor Keyzi Tomonaga from University of Osaka, Feskott assumes that similar impregnations are at the bottom of schizophrenia and other mental diseases of the person.
Born's virus received the name on the German city where in 1885 epidemic caused by it was fixed. This form энцефаломиелита almost completely exterminated horses of Prussian army, having turned its cavalry into infantry. Carriers of a virus of Born (BDV) are birds and house mammals, however long time was considered that this infection isn't dangerous to the person.
Only in 1996 the American physicians proved that Born's illness affects also people. Suffering this disease are subject to a constant depression, have memory problems, and also violation of perception of the outside world. Born's virus is in own way unique - his RNA sequence strikes only brain neurons, creating the permanent center of an infection in the carrier head.
Then the Taiwan geneticists showed that in families of the people struck with a virus of Born, the percent of patients with schizophrenia and other mental disorders is great. Now new research allowed to establish that the dangerous disease leaves the trace in a genome of the person, as provokes emergence of mental deviations in the subsequent generations.
Having investigated 234 enkriotichesky genomes (that is a genome which managed to be deciphered completely), Feskott and his colleagues found BDV signs in many mammals. Besides, geneticists found the mechanism allowing these RNA elements of a virus of Born to take root into chromosomes of the person, transferred this disease that conducts to the subsequent mutations of a nervous cage.
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